• Each pack of prescription medicine is given a unique serial number. This number is different for each pack (‘randomised’ = chosen at random).
• This serial number, together with the batch number (i.e. the production or lot number) and the expiry date, is encoded in a two-dimensional barcode on the package.
• The aim is to ensure that every package is uniquely identifiable within Europe.

• So that a package can be clearly traced in the supply chain — e.g. manufacturer → wholesaler → pharmacy/hospital → patient.
• To ensure that no counterfeit medicines enter the legal supply chain.

• When you receive a medicine, the serial number on the package is checked (‘verified’) – typically at the pharmacy, hospital or by a dispensing physician.
• During this process, the serial number is checked against a database system and then decommissioned (marked as supplied). This helps ensure that the medicine is genuine and has not been falsified.
• If any irregularities are detected during the verification process, the medicine must not be dispensed to the patient.

• The system is operated by the Austria Medicines Verification System GmbH (AMVS GmbH).
• It is a data storage and retrieval system for all prescription medicines marketed in Austria.
• The Austrian system is connected to a central EU hub, together with all EU countries, the European Economic Area (EEA) and Switzerland.

In addition to the serial number with barcode, each package must be equipped with a device (i.e tamper-evident seal) that indicates tampering with the outer packaging. In other words, it should be apparent whether the packaging has already been opened or altered.

• European Medicines Verification Organisation (EMVO)
• Austria Medicines Verification System GmbH (AMVS)